A chemoselective aniline–chloropyrimidine coupling in a competing electrophilic environment

doi:10.1016/J.TETLET.2007.11.009

Paper

A chemoselective aniline–chloropyrimidine coupling in a competing electrophilic environment

Published 2008 · A. Choudhury, Hongfeng Chen, Christopher N. Nilsen

Tetrahedron Letters

Q3 SJR score

23

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0

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Abstract

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Study Snapshot

This study demonstrates a highly chemoselective aniline-chloropyrimidine coupling, resulting in 4, 6-diaminopyrimidine-5-carbaldehyde in high yield, potentially involving imines.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

A chemoselective aniline–chloropyrimidine coupling in a competing electrophilic environment

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