Paper
COMPARATIVE ANTICONVULSIVE ACTION OF 3,5,5-TRIMETHYLOXAZOLIDINE-2,4-DIONE (TRIDIONE), DILANTIN AND PHENOBARBITAL
Published Aug 1, 1944 · G. Everett, R. K. Richards
The Journal of Pharmacology and Experimental Therapeutics
Q2 SJR score
137
Citations
3
Influential Citations
Abstract
1. The marked antagonistic action of 3,5,5-trimethyloxazolidine-2,4-dione (Tridione) against convulsions produced by drugs and electrical shock has been demonstrated in experimental animals. 2. Comparative experiments with phenobarbital and dilantin revealed that tridione is more comparable to phenobarbital in its action but produces less depression in effective doses.
Study Snapshot
Tridione effectively reduces drug-induced convulsions, more comparable to phenobarbital, but with less depression in effective doses.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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