The antidepressant-like effect of 7-fluoro-1,3-diphenylisoquinoline-1-amine in the mouse forced swimming test is mediated by serotonergic and dopaminergic systems

doi:10.1016/j.pnpbp.2014.06.001

Paper

The antidepressant-like effect of 7-fluoro-1,3-diphenylisoquinoline-1-amine in the mouse forced swimming test is mediated by serotonergic and dopaminergic systems

Published Oct 3, 2014 · A. Pesarico, T. B. Sampaio, E. C. Stangherlin

Progress in Neuro-Psychopharmacology and Biological Psychiatry

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Abstract

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Non-RCT

Animal Study

Study Snapshot

The antidepressant-like effect of 7-fluoro-1,3-diphenylisoquinoline-1-amine (FDPI) in mice is mainly mediated by serotonergic and dopaminergic systems.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

The antidepressant-like effect of 7-fluoro-1,3-diphenylisoquinoline-1-amine in the mouse forced swimming test is mediated by serotonergic and dopaminergic systems

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