Paper

Antikinetoplastid antimitotic activity and metabolic stability of dinitroaniline sulfonamides and benzamides.

Published Aug 15, 2006 · Tesmol G. George, Jayaseharan Johnsamuel, Dawn A. Delfín

Bioorganic & medicinal chemistry

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Abstract

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In Vitro Study

Study Snapshot

New dinitroaniline sulfonamide and benzamide analogs show promising in vitro antimitotic activity against kinetoplastid parasites, with some showing better in vivo activity than their parent compounds.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Antikinetoplastid antimitotic activity and metabolic stability of dinitroaniline sulfonamides and benzamides.

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