Antitumor agents. Part 3: synthesis and cytotoxicity of new trans-stilbene benzenesulfonamide derivatives.

doi:10.1016/S0960-894X(02)00092-6

Paper

Antitumor agents. Part 3: synthesis and cytotoxicity of new trans-stilbene benzenesulfonamide derivatives.

Published Apr 8, 2002 · Li-Ming Yang, Shwu-Jiuan Lin, F. Hsu

Bioorganic & medicinal chemistry letters

Q2 SJR score

22

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1

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Abstract

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In Vitro Study

Study Snapshot

New trans-stilbene benzenesulfonamide derivatives show potential as antitumor agents, with two showing selective cytotoxic activity against BT-549 breast cancer and HT-29 colon cancer.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Antitumor agents. Part 3: synthesis and cytotoxicity of new trans-stilbene benzenesulfonamide derivatives.

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References

Cancer Chemopreventive Activity of Resveratrol

Resveratrol shows potential as a cancer chemopreventive agent by inhibiting carcinogen-induced preneoplastic lesions and NF-B-induced gene expression, offering potential benefits for various disorders.

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Red wine, particularly red wine containing resveratrol and quercetin, effectively inhibits oral squamous carcinoma cell growth and DNA synthesis.

Resveratrol: a molecule whose time has come? And gone?

Resveratrol, found in red wine, has potential health benefits, but conclusive evidence on its absorption by humans in significant amounts remains unclear.

Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes

Resveratrol, a phytoalexin found in grapes, shows potential cancer chemopreventive activity through its antioxidant, antimutagenic, and anti-inflammatory effects.

SYNTHESIS AND ANTI-HIV ACTIVITY OF DIBENZYLBUTYROLACTONE LIGNANS

Dibenzylbutyrolactone lignans, specifically compounds 1 and 2, show anti-HIV replication activity with EC50 values of 2.2 and 0.16 g/ml, respectively.

Citations