Anxiolytic-like profile of mirtazapine in rat conditioned fear stress model: Functional significance of 5-hydroxytryptamine 1A receptor and α1-adrenergic receptor

doi:10.1016/j.pbb.2008.12.022

Paper

Anxiolytic-like profile of mirtazapine in rat conditioned fear stress model: Functional significance of 5-hydroxytryptamine 1A receptor and α1-adrenergic receptor

Published May 1, 2009 · Nobukazu Kakui, Fumikazu Yokoyama, Miki Yamauchi

Pharmacology Biochemistry and Behavior

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37

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Abstract

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Non-RCT

Animal Study

Study Snapshot

Mirtazapine shows anxiolytic-like effects in a rat conditioned fear stress model, involving activation of 5-HT1A receptor and 1 adrenoceptor to different extents.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Anxiolytic-like profile of mirtazapine in rat conditioned fear stress model: Functional significance of 5-hydroxytryptamine 1A receptor and α1-adrenergic receptor

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