Paper
Whole apple extracts increase lifespan, healthspan and resistance to stress in Caenorhabditis elegans.
Published Jul 1, 2013 · Elena M. Vayndorf, Siu Sylvia Lee, R. Liu
Journal of functional foods
Q1 SJR score
102
Citations
3
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Whole apple extracts extend lifespan, improve healthspan, and enhance resistance to stress in C. elegans, suggesting their potential as a dietary supplement.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
Full text analysis coming soon...
References
Pharmacological lifespan extension of invertebrates
Pharmacological lifespan extension of invertebrates, such as Caenorhabditis elegans, shows promise for discovering compounds that slow aging in humans.
2013·60citations·Mark Lucanic et al.·Ageing Research Reviews
Ageing Research Reviews
Theanine improves stress resistance in Caenorhabditis elegans
Theanine in tea can extend the lifespan of Caenorhabditis elegans under stress conditions, but not under normal conditions.
2012·16citations·Yushun Gong et al.·Journal of Functional Foods
Journal of Functional Foods
NIH Image to ImageJ: 25 years of image analysis
NIH Image and ImageJ software have been pioneers in open tools for scientific image analysis for 25 years, offering valuable insights for future software projects.
2012·51017citations·C. Schneider et al.·Nature Methods
Nature Methods
Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells
Dietary phytochemicals, such as polyphenols, can trigger DNA damage and repair mechanisms in cancer cells, potentially inducing apoptosis in cancer cells.
2011·193citations·P. Rajendran et al.·Clinical Epigenetics
Clinical Epigenetics
Apple Procyanidins Suppress Amyloid β-Protein Aggregation
Apple procyanidins show potential neuroprotective effects by suppressing amyloid -protein aggregation and inhibiting neurotoxicity in Alzheimer's disease models.
2011·35citations·Toshihiko Toda et al.·Biochemistry Research International
Biochemistry Research International
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