Paper

Assessment of subunit-dependent direct gating and allosteric modulatory effects of carisoprodol at GABAA receptors

Published Oct 1, 2015 · DOI · M. Kumar, L. A. González, G. Dillon

Neuropharmacology

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Abstract

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In Vitro Study

Study Snapshot

Carisoprodol has direct and allosteric effects at synaptic and extrasynpatic GABAA receptors, with subunit isoform influencing these effects.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Assessment of subunit-dependent direct gating and allosteric modulatory effects of carisoprodol at GABAA receptors

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