The association between anti-tumor potency and structure-activity of protein-kinases inhibitors based on quinazoline molecular skeleton.

doi:10.1016/j.bmc.2018.12.032

Paper

The association between anti-tumor potency and structure-activity of protein-kinases inhibitors based on quinazoline molecular skeleton.

Published Feb 1, 2019 · Yang Li, J. Xiao, Qizhi Zhang

Bioorganic & medicinal chemistry

Q2 SJR score

31

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1

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Abstract

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Study Snapshot

Quinazoline molecular skeletons are effective protein kinases inhibitors, with potential for improved anti-tumor drug design and improved clinical outcomes in cancer patients.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

The association between anti-tumor potency and structure-activity of protein-kinases inhibitors based on quinazoline molecular skeleton.

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