The current review describes the recent progress in the chemistry and biology of the benzhydryl amines where the central carbon atom is directly attached to the nitrogen atom of one ring and which have published in the last five years (2015–2019). Both metal and metal-free racemic and asymmetric synthetic approaches along with their activities as anti-leishmanial, antiviral, antibacterial, and anti-aromatase and other miscellaneous properties are discussed.

Recent progress in benzhydryl amine synthesis and biological activities suggests potential as anti-leishmanial, antiviral, antibacterial, and anti-aromatase agents.

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Benzhydryl Amines: Synthesis and Their Biological Perspective

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