Benzimidazol-Derivate und verwandte Heterocyclen III. Synthese von 1-Aminoalkyl-2-nenzyl-nitro-benzimidazolen

doi:10.1002/HLCA.19600430412

Paper

Benzimidazol-Derivate und verwandte Heterocyclen III. Synthese von 1-Aminoalkyl-2-nenzyl-nitro-benzimidazolen

Published 1960 · A. Hunger, J. Kebrle, A. Rossi

Helvetica Chimica Acta

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49

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1

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Abstract

The synthesis of a series of 1-aminoalkyl-2-benzyl-nitro-benzimidazoles is described. Many of the 5-nitro-benzimidazoles prepared show strong analgesic activity. 1-(β-Diethylamino-ethyl)-2-(p-ethoxy-benzyl)-5-nitro-benzimidazole (XXXVIII) is 1000 times as potent as morphine and therefore the most active analgesic known until now.

Study Snapshot

This study synthesised a series of 1-aminoalkyl-2-benzyl-nitro-benzimidazoles, with 1-(-Diethylamino-ethyl)-2-(p-ethoxy-benzyl)-5-nitro-benzimidazole

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Benzimidazol-Derivate und verwandte Heterocyclen III. Synthese von 1-Aminoalkyl-2-nenzyl-nitro-benzimidazolen

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References

Citations

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