Bile acid and sterol solubilization in 2-hydroxypropyl-beta-cyclodextrin.

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DOI:

Bile acid and sterol solubilization in 2-hydroxypropyl-beta-cyclodextrin.

Published Mar 1, 1992 · J. De Caprio, J. Yun, N. Javitt

Journal of lipid research

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Abstract

The use of 2-hydroxypropyl-beta-cyclodextrin has made it possible to prepare stable aqueous solutions of cholesterol, 26-hydroxycholesterol, 7 alpha-hydroxycholesterol, and monohydroxy bile acids such as lithocholic and 3 beta-hydroxy-5-cholenoic acids. These solutions are suitable for cell culture studies and for parenteral administration to animals.

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Study Snapshot

2-hydroxypropyl-beta-cyclodextrin effectively stabilizes cholesterol and bile acid solutions, making them suitable for cell culture studies and parenteral administration to animals.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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