Substituted aryl oxiranes undergo the facile ring opening with phenols in the presence of catalytic amount of bismuth(III) triflate to afford 1,3-diaryloxy-2-propanols in excellent yields under mild conditions. Bismuth(lll) triflate is relatively nontoxic, easy to handle and inexpensive, which makes this procedure particularly attractive for large scale synthesis.

Bismuth(III) triflate catalyzes facile ring opening of epoxides with phenols, leading to excellent yields of 1,3-diaryloxy-2-propanols under mild conditions.

Paper

Bi(OTf)(3)-catalyzed regioselective ring opening of epoxides with phenols: Facile synthesis of 1,3-diaryloxy-2-propanols

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