A variety of benzylic brominations were performed by using N-bromosuccinimide in (trifluoromethyl)benzene with photochemical activation in the presence of 2,2'-azobisisobutyronitrile, 1,1'-azobis(cyclohexanecarbonitrile), or benzoyl peroxide as the radical initiator. This system provides clean, rapid, and high-yielding reactions with replacement of conventional solvents, such as tetrachloromethane, by less-toxic (trifluoromethyl)benzene.

N-bromosuccinimide in (trifluoromethyl)benzene enables clean, rapid, and high-yielding benzylic brominations, using less-toxic solvents like (trifluoromethyl)benzene.

Paper

Benzylic Brominations with N‐Bromosuccinimide in (Trifluoromethyl)benzene.

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