Paper

Carbamazepine and oxcarbazepine, but not eslicarbazepine, enhance excitatory synaptic transmission onto hippocampal CA1 pyramidal cells through an antagonist action at adenosine A1 receptors

Published Jun 1, 2015 · Sam A. Booker, Nuno Pires, S. Cobb

Neuropharmacology

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCTAnimal Study

Study Snapshot

Carbamazepine and oxcarbazepine possess pro-epileptic actions at clinically-relevant concentrations by enhancing excitatory synaptic transmission, while eslicarbazepine has no such effect, explaining its lack of seizure exacerbation.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Carbamazepine and oxcarbazepine, but not eslicarbazepine, enhance excitatory synaptic transmission onto hippocampal CA1 pyramidal cells through an antagonist action at adenosine A1 receptors

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