Characterization of 4-methyl-2-oxo-1,2-dihydroquinolin-6-yl acetate as an effective antiplatelet agent.

doi:10.1016/j.bmc.2010.04.011

Paper

Characterization of 4-methyl-2-oxo-1,2-dihydroquinolin-6-yl acetate as an effective antiplatelet agent.

Published Jun 1, 2010 · N. Priya, Anjali Gupta, K. Chand

Bioorganic & medicinal chemistry

Q2 SJR score

25

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1

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Abstract

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In Vitro Study

Study Snapshot

Acetoxy quinolones, specifically 6-AQ, effectively inhibit platelet aggregation by activating platelet Nitric Oxide Synthase through acetylation, with structural modifications enhancing antiplatelet activity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Characterization of 4-methyl-2-oxo-1,2-dihydroquinolin-6-yl acetate as an effective antiplatelet agent.

References

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