Chloromycetin (chloramphenicol) in the treatment of infections.

doi:10.1056/NEJM195001262420402

Paper

Chloromycetin (chloramphenicol) in the treatment of infections.

Published Jan 26, 1950 · W. Hewitt, B. Williams

The New England journal of medicine

33

Citations

0

Influential Citations

Full text

Abstract

CHLOROMYCETIN (chloramphenicol) is a white crystalline antibiotic agent isolated originally from Streptomyces venezuelae.1 The chemical formula has been determined,2 and the manufacture of the compound by chemical synthesis has been accomplished on a commercially practicable basis. It is an extremely bitter material, relatively stable in water over a wide range of temperature and pH and sparingly soluble in water to the extent of 2.5 mg. per cubic centimeter. Previous studies have shown Chloromycetin to be active against a wide spectrum of bacteria in vitro, including many gram-positive cocci, the gonococcus and most of the gram-negative bacilli except certain strains . . .

Study Snapshot

Chloromycetin (chloramphenicol) is a highly effective antibiotic agent that effectively treats infections caused by a wide spectrum of bacteria, including gram-positive cocci, gonococcus, and most gram-negative bacilli except certain strains.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Chloromycetin (chloramphenicol) in the treatment of infections.

References

Citations