Chloroquine impairs the interferon-induced antiviral state without affecting the 2',5'-oligoadenylate synthetase.

doi:10.1016/s0021-9258(17)39546-7

Paper

Chloroquine impairs the interferon-induced antiviral state without affecting the 2',5'-oligoadenylate synthetase.

Published Jul 5, 1985 · M. Chelbi-alix, M. N. Thang

The Journal of biological chemistry

Q1 SJR score

9

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1

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Abstract

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In Vitro Study

Study Snapshot

Chloroquine impairs the interferon-induced antiviral state by raising the pH in acidic cellular compartments, suggesting a low pH-dependent event in interferon's intracellular fate is necessary for antiviral state establishment.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Chloroquine impairs the interferon-induced antiviral state without affecting the 2',5'-oligoadenylate synthetase.

References

Citations