Comparison of the effects of sodium sulfate and N-acetylcysteine on the hepatotoxicity of acetaminophen in mice.

doi:10.1016/s0022-3565(25)38918-4

Paper

Comparison of the effects of sodium sulfate and N-acetylcysteine on the hepatotoxicity of acetaminophen in mice.

Published Feb 1, 1986 · J. Hjelle, E. Brzeźnicka, C. Klaassen

The Journal of pharmacology and experimental therapeutics

Q2 SJR score

23

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Study Snapshot

Sodium sulfate increases serum sulfate concentration and hepatic adenosine 3'-phosphate 5'-phosphosulfate levels but does not protect against acetaminophen-induced hepatotoxicity in mice.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

Paper

Comparison of the effects of sodium sulfate and N-acetylcysteine on the hepatotoxicity of acetaminophen in mice.

Sign up to use Study Snapshot

References

Citations

Advances in the understanding of acetaminophen toxicity mechanisms: a clinical toxicology perspective

Advances in understanding acetaminophen toxicity mechanisms have led to the development of novel biomarkers and improved understanding of the role of proposed adjunct treatments in prevention and treatment.

Rosemary (Rosmarinus officinalis L.) Glycolic Extract Protects Liver Mitochondria from Oxidative Damage and Prevents Acetaminophen-Induced Hepatotoxicity

Rosemary glycolic extract protects liver mitochondria from oxidative damage and prevents acetaminophen-induced hepatotoxicity in rats.

antioxidants

Honeydew and blossom honeys can be satisfactorily discriminated using Folin-Ciocalteu index, total flavonoid content, and FRAP assays, with blossom honeys being easily classified by their botanical origin.

Assessment of Renal and Hepatic Tissue-Protective Effects of N-Acetylcysteine via Ammonia Metabolism: A Prospective Randomized Study

N-acetylcysteine pretreatment improves renal and hepatic functions by regulating ammonia and nitrogen metabolism and reducing lactate in patients with chronic obstructive pulmonary disease undergoing coronary artery bypass grafting surgery.

Acetaminophen-induced differentiation of human breast cancer stem cells and inhibition of tumor xenograft growth in mice.

Acetaminophen may benefit breast cancer chemotherapy by inducing differentiation of cancer stem cells, increasing susceptibility to anti-tumor drugs, and inhibiting tumor xenograft growth in mice.