New compounds: derivatives of methyl 2-aminoacetyl-4,5-dimethoxyphenylacetate.

doi:10.1002/JPS.2600650444

Paper

New compounds: derivatives of methyl 2-aminoacetyl-4,5-dimethoxyphenylacetate.

Published Apr 1, 1976 · P. Catsoulacos

Journal of pharmaceutical sciences

Q2 SJR score

2

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0

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Abstract

Methyl 2-bromoacetyl-4,5-dimethoxyphenylacetate was prepared by reacting cupric bromide with methyl 2-acetyl-4,5-dimethoxyphenylacetate. Aminoacetyl derivatives formed on condensation of substituted p-aminobenzoic esters with the bromoacetyl derivative. Some prepared compounds were tested for local anesthetic and anti-inflammatory activities.

Study Snapshot

Methyl 2-aminoacetyl-4,5-dimethoxyphenylacetate derivatives show potential as local anesthetics and anti-inflammatory agents.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Paper

New compounds: derivatives of methyl 2-aminoacetyl-4,5-dimethoxyphenylacetate.

References

Citations

The pyrrolo[2,1-a]isoquinoline alkaloids.

The pyrrolo[2,1-a]isoquinoline alkaloids show promising biological activities, with many total syntheses reported for crispine A and trolline (3), but some have not been synthesized yet.