Paper

Consequences of inhibition of purine biosynthesis de novo by 6-methylmercaptopurine ribonucleoside in cultured lymphoma L5178Y cells.

Published Jul 1, 1978 · DOI · R. A. Woods, R. M. Henderson, J. Henderson

European journal of cancer

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Abstract

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Study Snapshot

6-methylmercaptopurine ribonucleoside inhibits purine biosynthesis and causes growth inhibition and cell death in cultured lymphoma L5178Y cells, leading to decreased purine and pyrimidine concentrations.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Consequences of inhibition of purine biosynthesis de novo by 6-methylmercaptopurine ribonucleoside in cultured lymphoma L5178Y cells.

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