Construction of 3-amino-2-oxindoles by direct amination of aniline or α-amino-acid derivatives to 3-bromooxindoles

doi:10.1016/J.TET.2016.01.039

Paper

Construction of 3-amino-2-oxindoles by direct amination of aniline or α-amino-acid derivatives to 3-bromooxindoles

Published Mar 10, 2016 · Min-Min Zhao, Naiying Li, Ya-Fei Zhang

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Abstract

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Study Snapshot

Direct amination of anilines or -amino-acid derivatives to 3-bromooxindoles can produce enantiomerically enriched 3-amino-2-oxindoles with quaternary stereocenters in up to 90% yield.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Construction of 3-amino-2-oxindoles by direct amination of aniline or α-amino-acid derivatives to 3-bromooxindoles

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