Cordyceps Mushroom: A Potent Anticancer Nutraceutical

doi:10.2174/18763960010030100179

Paper

Cordyceps Mushroom: A Potent Anticancer Nutraceutical

Published Apr 30, 2010 · Md. Asaduzzaman Khan, Mousumi Tania, Dianzheng Zhang

The Open Nutraceuticals Journal

UNKNOWN SJR score

61

Citations

2

Influential Citations

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Abstract

The Cordyceps mushrooms have a long history as medicinal fungi. In Traditional Chinese Medicine, Cordyceps have been used to treat several conditions including cancers for thousand of years. Extracts from both mycelium and fruiting bodies of C. sinensis, C. militaris and other Cordyceps species showed significant anticancer activities by various mechanisms such as, modulating immune system and inducing cell apoptosis. Some polysaccharide components and cordycepin (3'-deoxyadenosine) have been isolated from C. sinensis and C. militaris, which acted as potent anticancer components. This review article aims to further elucidate the importance of Cordyceps mushrooms by summarizing the findings of some of the important research works concerning possible mechanism of anticancer activity of this mushroom.

Literature Review

Study Snapshot

Cordyceps mushrooms show significant anticancer activities by modulating immune system and inducing cell apoptosis, with polysaccharide components and cordycepin acting as potent components.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Cordyceps Mushroom: A Potent Anticancer Nutraceutical

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References

Citations

Application and research progress of cordycepin in the treatment of tumours (Review)

Cordycepin, found in Cordyceps sinensis, shows antitumor activity and enhances the therapeutic effects of radiotherapy, making it a promising treatment for various cancers.

Chemopreventive Role of Proteins and Polysaccharides from Pleurotus tuber-regium

Proteins and polysaccharides from Pleurotus tuber-regium mushrooms show potential as cytotoxic agents against various cancer cell lines, potentially improving the body's defenses against cancers without destroying normal cells.

Cordyceps sensu lato: the current state of knowledge in Mexico

35 species of Cordyceps s.l. have been recorded in Mexico, with Beauveria bassiana and Metarhizium anisopliae being the most studied due to their pathogenicity to crop pests.

Cordycepin and kinase inhibition in cancer.

Cordycepin, a nucleoside from Cordyceps mushrooms, may have anticancer properties by targeting and disrupting various kinases involved in cancer development and progression.

Synthesis and Characterization of NUC-7738, an Aryloxy Phosphoramidate of 3′-Deoxyadenosine, as a Potential Anticancer Agent

NUC-7738, a 5′-aryloxy phosphoramidate of 3′-deoxyadenosine, shows potential as an effective anticancer drug with preferential cytotoxic effects on leukemic stem cells and resistance to ADA metabolic deactivation.