Cycloaddition of 6-hydroxy-2,6-dimcthylcyclohexa-2,4-dienones with ethyl vinyl ether, butyl vinyl ether, vinyl acetate and vinyl phenyl sulphone leading to a stereoselective entry into bicyclo[2.2.2]octanes having quaternary methyl group is reported. A novel thermal 1,2-methyl migration has also been described.

This study demonstrates a novel 1,2-methyl migration in bicyclo[2.2.2]octanes by cycloaddition of 6-hydroxy-2,6-dimethylcyclohexa-2,4-dienones with ethyl vinyl ether, butyl vinyl ether

ChemInform

Cycloaddition of 6-Hydroxy-2,6-dimethylcyclohexa-2,4-dienone: A Stereoselective Entry into Functionalized Bicyclo[2.2.2]octanes and a Novel 1,2-Migration of Methyl Group.

Paper

Cycloaddition of 6-Hydroxy-2,6-dimethylcyclohexa-2,4-dienone: A Stereoselective Entry into Functionalized Bicyclo[2.2.2]octanes and a Novel 1,2-Migration of Methyl Group.

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