Paper

Cytotoxic effects of crotamine are mediated through lysosomal membrane permeabilization.

Published Sep 1, 2008 · M. Hayashi, F. D. Nascimento, A. Kerkis

Toxicon : official journal of the International Society on Toxinology

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Abstract

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In Vitro StudyHighly Cited

Study Snapshot

Crotamine's cytotoxic effects are primarily mediated through disruption of lysosomal membranes, suggesting that its cytotoxicity may not be limited to muscle cells.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Cytotoxic effects of crotamine are mediated through lysosomal membrane permeabilization.

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