Design, synthesis and biological activity of N-(2-phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamides as new antitubercular agents.

doi:10.1016/j.ejmech.2019.06.038

Paper

Design, synthesis and biological activity of N-(2-phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamides as new antitubercular agents.

Published Sep 15, 2019 · A-peng Wang, Kai Lv, Linhu Li

European journal of medicinal chemistry

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29

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Abstract

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In Vitro Study

Study Snapshot

N-(2-phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamides show promising potential as new anti-TB agents with excellent in vitro inhibitory activity and good safety and pharmacokinetic profiles.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Design, synthesis and biological activity of N-(2-phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamides as new antitubercular agents.

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