Design, synthesis and antimicrobial activity of novel 2-aminothiophene containing cyclic and heterocyclic moieties.

doi:10.1016/j.bmcl.2021.128117

Paper

Design, synthesis and antimicrobial activity of novel 2-aminothiophene containing cyclic and heterocyclic moieties.

Published May 17, 2021 · Y. Asiri, A. Muhsinah, A. Alsayari

Bioorganic & medicinal chemistry letters

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12

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Abstract

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In Vitro Study

Study Snapshot

2-aminothiophene derivatives show promising antimicrobial activity against various bacteria and fungi, with compounds 3a showing stronger antibacterial activity than Ampicillin and Gentamicin.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Design, synthesis and antimicrobial activity of novel 2-aminothiophene containing cyclic and heterocyclic moieties.

References

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