Paper

Design, synthesis and anticancer activities evaluation of novel 5H-dibenzo[b,e]azepine-6,11-dione derivatives containing 1,3,4-oxadiazole units.

Published Mar 1, 2018 · Xin He, Xin-Yang Li, Jing-wei Liang

Bioorganic & medicinal chemistry letters

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Abstract

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In Vitro Study

Study Snapshot

Novel 5H-dibenzo[b,e]azepine-6,11-dione derivatives with 1,3,4-oxadiazole units show better anti-proliferative effects against OVCAR-3 cells than Rucaparib.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Design, synthesis and anticancer activities evaluation of novel 5H-dibenzo[b,e]azepine-6,11-dione derivatives containing 1,3,4-oxadiazole units.

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