Paper
Designing analogs of ticlopidine, a wall teichoic acid inhibitor, to avoid formation of its oxidative metabolites.
Published Feb 1, 2014 · Maya A. Farha, K. Koteva, R. T. Gale
Bioorganic & medicinal chemistry letters
Q2 SJR score
25
Citations
0
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
In Vitro StudyStudy Snapshot
Stable analogs of ticlopidine and clopidogrel can effectively inhibit TarO, enhancing their antiplatelet effects and reducing oxidative metabolism in the human body.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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Citations
The anti-platelet drug ticlopidine inhibits FapC fibrillation and biofilm production: Highlighting its antibiotic activity.
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