Pyrazole, Pyridine, and oxadiazole are important scaffolds because of having medicinal applications like anticonvulsant, hypoglycemia, molluscicidal, stimulant, and anticancer, etc. At present, to achieve a highly potent molecule we have synthesized a novel series of pyrazole bearing 1,3,4-oxadiazole heterocycles 4a–o (1-(3,5-substituted-diphenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)ethan-1-one) were and characterized by mass spectroscopy, 1H and 13C NMR spectroscopy, and Infrared spectroscopy. All synthesized compounds were evaluated against gram-positive and gram-negative bacterial strains.

Pyrazole integrated oxadiazole derivatives show potential as antibacterial agents against both gram-positive and gram-negative bacteria.

Paper

Synthesis and Antibacterial Evaluation of Pyrazole Integrated Oxadiazole Derivatives

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