Paper
Deuterium-labeled 3-nitrobenzyl alcohol as a matrix for fast atom bombardment mass spectrometry.
Published Dec 1, 1989 · A. Mahender Reddy, Victoria V. Mykytyn, Karl H. Schram
Biomedical & environmental mass spectrometry
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Abstract
The utility of deuterium-labeled 3-nitrobenzyl alcohol (DNBA) as a fast atom bombardment (FAB) matrix for establishing the number of exchangeable hydrogens present in a molecule is illustrated by the analysis of five selected antitumor agents. A method for the simple preparation of this labeled matrix is described. The use of DNBA may be of value for samples which provide no FAB spectra when deuterium-labeled glycerol is used as a matrix.
Deuterium-labeled 3-nitrobenzyl alcohol (DNBA) is a useful matrix for fast atom bombardment mass spectrometry, enabling the analysis of antitumor agents when deuterium-labeled glycerol fails to provide spectra.
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