Differentiation of the mechanisms of oncogenicity of 1,4-dioxane and 1,3-hexachlorobutadiene in the rat.

doi:10.1016/0041-008X(91)90232-4

Paper

Differentiation of the mechanisms of oncogenicity of 1,4-dioxane and 1,3-hexachlorobutadiene in the rat.

Published Sep 15, 1981 · W. Stott, J. Quast, P. Watanabe

Toxicology and applied pharmacology

Q2 SJR score

73

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5

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Highly Cited

Study Snapshot

1,4-dioxane induces liver tumors through a nongenetic mechanism, while 1,3-hexachlorobutadiene causes kidney tumors primarily through a nongenetic mechanism, with minor genetic contributions.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Differentiation of the mechanisms of oncogenicity of 1,4-dioxane and 1,3-hexachlorobutadiene in the rat.

References

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