Paper

Disruption of LH-induced testosterone biosynthesis in testicular Leydig cells by triclosan: probable mechanism of action.

Published Sep 4, 2008 · Vikas Kumar, C. Balomajumder, P. Roy

Toxicology

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Abstract

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In Vitro StudyHighly Cited

Study Snapshot

Triclosan disrupts testosterone production in testicular Leydig cells by decreasing adenylyl cyclase activity and disrupting the intermediate steroidogenic cascade.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Disruption of LH-induced testosterone biosynthesis in testicular Leydig cells by triclosan: probable mechanism of action.

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