DMPM (3,4-dimethoxybenzyl) protecting group for hydroxy function more readily removable than MPM (P-methoxybenzyl) protecting group by DDQ oxidation

doi:10.1016/S0040-4039(01)91293-6

Paper

DMPM (3,4-dimethoxybenzyl) protecting group for hydroxy function more readily removable than MPM (P-methoxybenzyl) protecting group by DDQ oxidation

Published Mar 5, 1985 · Y. Oikawa, Tatsuyoshi Tanaka, K. Horita

Tetrahedron Letters

Q3 SJR score

60

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Study Snapshot

DMPM (3,4-dimethoxybenzyl) protection for hydroxy function is more readily removable than MPM (P-methoxybenzyl) protection by DDQ oxidation under neutral conditions, aiding in the synthesis of macrolide and polyether antibiotics.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

Paper

DMPM (3,4-dimethoxybenzyl) protecting group for hydroxy function more readily removable than MPM (P-methoxybenzyl) protecting group by DDQ oxidation

Sign up to use Study Snapshot

References

Kinetic acetalization for 1,2- and 1,3-diol protection by the reaction of p-methoxyphenylmethyl methyl ether with DDQ

Kinetic acetalization of 1,2- and 1,3-diols with p-methoxyphenylmethyl ether and DDQ effectively protects these compounds, even with acid-labile compounds.

Protection of hydroxy groups by intramolecular oxidative formation of methoxybenzylidene acetals with DDQ

Intramolecular oxidative formation of methoxybenzylidene acetals with DDQ effectively protects hydroxy groups at or positions, leading to alkali-sensitive hydroxy esters in the presence of H 2 O.

Specific removal of o-methoxybenzyl protection by DDQ oxidation.

DDQ oxidation efficiently removes o-methoxybenzyl protecting groups from alcohols, while maintaining other protecting groups and functional groups.

Citations

Spatially Selective Electrochemical Cleavage of a Polymerase-Nucleotide Conjugate

This study developed a polymerase-nucleotide conjugate that can be cleaved using electrochemical oxidation on a microelectrode array, enabling parallel enzymatic DNA synthesis for DNA data storage and gene synthesis.

Synthesis and biological activity of ganglioside GM3 analogues with a (S)-CHF-Sialoside linkage and an alkyne tag

The growth-promoting effect of ganglioside GM3 analogues with an alkyne tag on Had-1 cells is significantly altered depending on the position of the alkyne tag.

DDQ as a versatile and easily recyclable oxidant: a systematic review

DDQ is a versatile and easily recyclable oxidant for organic synthesis, with applications in functionalization, dehydrogenation, and deprotection of p-methoxybenzyl ethers.

Total synthesis of the actinoallolides and a designed photoaffinity probe for target identification.

Actinoallolides show potent biological activity against trypanosomes, aiding in the identification of their protein binding targets for potential therapeutic use in treating human African trypanosomiasis and Chagas disease.

Quinone-Catalyzed Selective Oxidation of Organic Molecules.

Quinone-catalyzed selective oxidation of organic molecules reveals that the quinone structure significantly influences the reaction mechanism and has implications for the development of new reagents and catalyzed transformations.