Paper

DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

Published Dec 23, 2002 · M. Robert, Steves Morin, N. Beaulieu

Nature Genetics

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro StudyHighly Cited

Study Snapshot

DNMT1 is necessary and sufficient to maintain global methylation and aberrant CpG island methylation in human cancer cells, affecting gene silencing and promoting tumor growth.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

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