Paper

Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?

Published Apr 12, 2021 · DOI · C. Akdis

Nature Reviews Immunology

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Abstract

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Study Snapshot

The epithelial barrier hypothesis suggests that increased exposure to epithelial barrier-damaging agents due to industrialization, urbanization, and modern life contributes to the rise in allergic, autoimmune, and other chronic conditions.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?

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