Double-blind placebo-controlled evaluation of sublingual-swallow immunotherapy with standardized Parietaria judaica extract in children with allergic rhinoconjunctivitis.

doi:10.1016/S0091-6749(99)70388-X

Paper

Double-blind placebo-controlled evaluation of sublingual-swallow immunotherapy with standardized Parietaria judaica extract in children with allergic rhinoconjunctivitis.

Published Aug 1, 1999 · M. L. Rosa, Carmen Ranno, C. André

The Journal of allergy and clinical immunology

Q1 SJR score

228

Citations

8

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Abstract

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Study Snapshot

Sublingual-swallow immunotherapy with standardized Parietaria judaica extract effectively reduces rhinitis symptoms and decreases specific reactivity in children with Parietaria-induced rhinoconjunctivitis, with good tolerance and compliance.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Double-blind placebo-controlled evaluation of sublingual-swallow immunotherapy with standardized Parietaria judaica extract in children with allergic rhinoconjunctivitis.

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References

Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper.

Allergen immunotherapy is an effective treatment for allergic diseases, with new techniques and research recommendations aiming to improve safety and efficacy.

Double‐blind, placebo‐controlled evaluation of sublingual immunotherapy with standardized olive pollen extract in pediatric patients with allergic rhinoconjunctivitis and mild asthma due to olive pollen sensitization

High-dose specific sublingual immunotherapy is safe and effective in improving mild seasonal asthma and conjunctivitis linked to olive pollen sensitization in children.

Pollen‐related allergy in Europe *

Pollen-related allergies in Europe are mainly caused by grass pollen, with cultural factors and international travel influencing the pollen map.

Immunotherapy as an effective tool in allergy treatment

Allergen-specific immunotherapy and allergen reduction are effective treatments for allergic diseases, with immunotherapy being the only option for long-term symptom reduction and pharmacotherapy having limited long-term efficacy.

Clinical efficacy of sublingual‐swallow immunotherapy: a double‐blind, olacebo‐controlled trial of a standardized five‐grass‐pollen extract in rhinitis

Sublingual-swallow immunotherapy (SLIT) effectively reduces medication consumption and the need for oral corticosteroids in patients with grass-pollen rhinitis, while maintaining overall clinical symptoms.

Citations

Efficacy and safety of sublingual versus subcutaneous immunotherapy in children with allergic rhinitis: a systematic review and meta-analysis

Sublingual immunotherapy (SLIT) is as effective and safe as subcutaneous immunotherapy (SCIT) in children with allergic rhinitis, with a significantly lower incidence of asthma development.

Mechanisms of Allergen Immunotherapy and Potential Biomarkers for Clinical Evaluation

Allergen-immunotherapy (AIT) effectively treats IgE-mediated diseases, with potential biomarkers aiding in patient selection and care during treatment.

Immune mechanisms induced by sublingual immunotherapy in allergic respiratory diseases

Sublingual immunotherapy (SLIT) reduces eosinophilia and inflammation in airways, and may shift immune responses towards protective regulation in allergic respiratory diseases.

Pediatric sublingual allergen immunotherapy.

Sublingual immunotherapy (SLIT) is effective in reducing symptoms and medication use for children with respiratory allergies, but its role in prevention of new sensitizations and asthma remains unclear.

Sublingual Immunotherapy: How Sublingual Allergen Administration Heals Allergic Diseases; Current Perspective about the Mode of Action

Sublingual immunotherapy (SLIT) effectively treats allergic diseases by inducing blocking antibodies, T cell tolerance, regulatory B and T cells, and reducing innate lymphoid cells, mast cells, and basophils.