Paper

H(1) antihistamine drug promethazine directly blocks hERG K(+) channel.

Published Nov 1, 2009 · S. Jo, Hee-Kyung Hong, Seon-Ha Chong

Pharmacological research

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Study Snapshot

Promethazine is a blocker of hERG channels, providing a molecular mechanism for its arrhythmogenic side effects during clinical administration.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

H(1) antihistamine drug promethazine directly blocks hERG K(+) channel.

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