Paper

The effect of 3,4-dimethyl substitution on the neurotoxicity of 2,5-hexanedione. I. Accelerated clinical neuropathy is accompanied by more proximal axonal swellings.

Published Dec 1, 1983 · DOI · D. Anthony, Kim Boekelheide, C. Anderson

Toxicology and applied pharmacology

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCTAnimal StudyHighly Cited

Study Snapshot

The 3,4-dimethyl-2,5-hexanedione compound is 20-30 times more potent and causes more proximal neurofilamentous swellings, suggesting a common mechanism of injury for neurofilament neuropathies.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

The effect of 3,4-dimethyl substitution on the neurotoxicity of 2,5-hexanedione. I. Accelerated clinical neuropathy is accompanied by more proximal axonal swellings.

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