Neuroprotective effect of 4-hydroxybenzyl alcohol against transient focal cerebral ischemia via anti-apoptosis in rats

doi:10.1016/j.brainres.2009.10.037

Paper

Neuroprotective effect of 4-hydroxybenzyl alcohol against transient focal cerebral ischemia via anti-apoptosis in rats

Published Jan 13, 2010 · Shan-shan Yu, Jing Zhao, Weiping Zheng

Brain Research

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86

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0

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

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Study Snapshot

4-hydroxybenzyl alcohol (4-HBA) effectively reduces infarct volumes and improves neurological evaluation in rats with transient focal cerebral ischemia, partly due to its ability to inhibit apoptosis.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Neuroprotective effect of 4-hydroxybenzyl alcohol against transient focal cerebral ischemia via anti-apoptosis in rats

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References

Experimental stroke protection induced by 4-hydroxybenzyl alcohol is cancelled by bacitracin

4-hydroxybenzyl alcohol, found in Gastrodia elata Blume, effectively reduces cerebral infarct volumes by 55%, making it a valuable target for brain injury control.

Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee.

The 2009 Heart Disease and Stroke Statistical Update provides the most up-to-date statistics on heart disease, stroke, and their risk factors for researchers, clinicians, healthcare policy makers, and the public.

Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee.

The 2009 Heart Disease and Stroke Statistical Update provides the most up-to-date statistics on heart disease, stroke, and their risk factors for researchers, clinicians, healthcare policy makers, and the public.

Vanillin, 4-hydroxybenzyl aldehyde and 4-hydroxybenzyl alcohol prevent hippocampal CA1 cell death following global ischemia

Vanillin, 4-hydroxybenzyl aldehyde, and 4-hydroxybenzyl alcohol show neuroprotective effects in the hippocampal CA1 region after global ischemia, potentially benefiting stroke patients.

Protective effects of several components of Gastrodia elata on lipid peroxidation in gerbil brain homogenates

Gastrodia elata extract and its main constituents show excellent antioxidant effects, potentially benefiting lipid peroxidation-associated neurological diseases.

Citations