Paper
Effect of chrysin on hepatoprotective and antioxidant status in D-galactosamine-induced hepatitis in rats.
Published Apr 10, 2010 · G. Pushpavalli, P. Kalaiarasi, C. Veeramani
European journal of pharmacology
Q1 SJR score
178
Citations
6
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Non-RCT
Animal Study
Highly CitedStudy Snapshot
Chrysin acts as a hepatoprotective and antioxidant agent against D-galactosamine-induced hepatotoxicity in rats, decreasing enzyme activities and lipid peroxidation.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
Spectroscopic investigation of the interaction between chrysin and bovine serum albumin
The interaction between chrysin and bovine serum albumin is driven mainly by hydrophobic interaction, with chrysin causing a conformational change in BSA.
2009·102citations·Guowen Zhang et al.·Journal of Molecular Structure
Journal of Molecular Structure
Interaction of flavonoids with red blood cell membrane lipids and proteins: antioxidant and antihemolytic effects.
Plant flavonoids binding to red blood cell membranes significantly inhibit lipid peroxidation and enhance their integrity against hypotonic lysis, with their antioxidant and antihemolytic activities depending on their locations in the membrane matrix.
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International journal of biological macromolecules
Quercetin decreases oxidative stress, NF-kappaB activation, and iNOS overexpression in liver of streptozotocin-induced diabetic rats.
Quercetin treatment reduces oxidative stress, NF-kappaB activation, and iNOS overexpression in streptozotocin-induced diabetic rats, potentially preventing early diabetes tissue injury and late complications.
2005·349citations·A. Dias et al.·The Journal of nutrition
The Journal of nutrition
Free radical scavenging and hepatoprotective activity of jigrine against galactosamine induced hepatopathy in rats.
Jigrine, a herbal formulation containing 14 medicinal plants, exhibits significant hepatoprotective activity against galactosamine-induced hepatopathy in rats, similar to that of Silymarin.
2005·72citations·A. Najmi et al.·Journal of ethnopharmacology
Journal of ethnopharmacology
Effects of Chronic Chrysin Treatment in Spontaneously Hypertensive Rats
Chronic chrysin treatment reduces elevated blood pressure, cardiac hypertrophy, and functional vascular changes in spontaneously hypertensive rats, but has no effect on normotensive rats.
2002·63citations·I. Villar et al.·Planta Medica
Planta Medica
Citations
The integration of metabolites from Forsythia suspensa and gut microbiota ameliorates drug-induced liver injury: network pharmacology and molecular docking studies.
Metabolites from Forsythia suspensa and gut microbiota may have a potent synergistic effect on drug-induced liver injury by modulating the estrogen signaling pathway.
2025·0citations·Yanni Wang et al.·Artificial cells, nanomedicine, and biotechnology
Artificial cells, nanomedicine, and biotechnology
Chrysin analysis by QuEChERS modified method and HPLC-DAD, antioxidant potential and in vitro gastrointestinal digestion of Passiflora caerulea
The QuEChERS modified method and HPLC-DAD effectively analyze chrysin in Passiflora species, with leaves and green peel showing the highest chrysin content and antioxidant potential.
2025·0citations·Carlos Borges Filho et al.·South African Journal of Botany
South African Journal of Botany
Anti-melanogenic effects of hydroxyethyl chrysin through the inhibition of tyrosinase activity: In vitro and in silico approaches
HE-chrysin shows potential as an anti-melanogenic candidate and antioxidant for dermatologic therapy by suppressing tyrosinase activity without cytotoxicity.
2025·0citations·Yuna Lee et al.·Heliyon
Heliyon
Cyclophosphamide-induced testicular injury: the role of chrysin in mitigating iron overload and ferroptosis.
Chrysin effectively counteracts cyclophosphamide-induced testicular toxicity in rats, restoring hormonal balance and reducing inflammation, apoptosis, and iron-regulatory protein suppression.
2024·0citations·Dalia O. Saleh et al.·Naunyn-Schmiedeberg's archives of pharmacology
Naunyn-Schmiedeberg's archives of pharmacology
Binding investigation of chrysin and flavone with promoter DNA sequence d(CACGTG)2: Multi spectroscopic studies and cytotoxic evaluation
Chrysin and flavone show significant antiproliferation effects against MCF-7, DU-145, and HCT-15 cancer cell lines, with flavone being more effective against prostate cancer cells.
2024·1citation·Shailendra Kumar et al.·Journal of Molecular Structure
Journal of Molecular Structure
Metabolite profiling and wound healing potential of Gynura cusimbua in zebrafish model
Gynura cusimbua hydroalcoholic extract shows wound healing potential and no developmental toxicity in zebrafish models, with potential therapeutic applications.
2024·0citations·Anuradha Moirangthem et al.·Advances in Traditional Medicine
Advances in Traditional Medicine
Property-Wound Healing Relationship of Manuka-, Anzer- and Chestnut-Honey: Characterization, Antibacterial Properties and Cell Culture Applications
Turkish Chestnut and Anzer honeys show comparable wound healing properties to Manuka honey, making them promising candidates for clinical applications.
2024·0citations·A. Ünlü et al.·Turkish Journal of Agriculture - Food Science and Technology
Turkish Journal of Agriculture - Food Science and Technology
Co-encapsulation of two antidepressant agents, Lactiplantibacillus plantarum and chrysin flavonoid, by external ionic gelation: Feasibility, properties and stability
Co-encapsulation of Lactiplantibacillus plantarum and chrysin flavonoid by external ionic gelation is feasible, providing progressive release of probiotics in the digestive tract and protecting chrysin from degradation in the gastric phase.
2024·1citation·Carlos Borges Filho et al.·Journal of Drug Delivery Science and Technology
Journal of Drug Delivery Science and Technology