Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats

doi:10.1016/j.neuroscience.2010.08.039

Paper

Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats

Published Nov 24, 2010 · H. Kalonia, P. Kumar, A. Kumar

Neuroscience

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43

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Rigorous Journal

Study Snapshot

Montelukast shows neuroprotective potential in managing Huntington's like symptoms in rats by reducing behavioral alterations, oxidative stress, mitochondrial dysfunction, and TNF- levels.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats

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