Paper
Effect of Watermelon (Citrullus lanatus) Flesh Extract on Sexual Behavior of Male Rats
Published Jan 1, 2014 · DOI · P. Munglue, S. Kupittayanant, P. Kupittayanant
Chiang Mai University journal of natural sciences
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Abstract
The effects of red watermelon (Citrullus lanatus) flesh extract on male sexual behavior as well as its adverse effects were investigated using animal models. The suspension of the flesh extract was administered orally at doses of 100, 500 and 1000 mg/kg to different groups of male rats (n = 5) daily for 22 days. The receptive female rats were prepared by hormonal treatment. The mat- ing behavior was investigated and compared with the standard reference drug, sildenafil citrate. The adverse effects of the plant extract were also evaluated by observing at least once daily for any sign of toxicity, water and food intake, stress and changes in behavior. The animal procedures were conducted in accordance with the Institutional Animal Care and Use Committee, Ubon Ratchathani Ra- jabhat University, Thailand. The results indicated that oral administration of watermelon flesh extract caused a significant increase in Mounting Frequency, Intromission Frequency and Ejaculatory Latency in first and second series and caused a significant decrease in the Mounting Latency and Intromission Latency (P 0.05). Based on the aphrodisiac property of watermelon in animal models observed in this present study, this plant may be useful for men with erectile dysfunction. In addition, watermelon flesh extract did not produce undesirable effects on male rats, indi- cating that its short-term use is apparently safe. Thus, our findings support the use of watermelon flesh for increasing potency in males.
Watermelon flesh extract significantly increases sexual behavior in male rats, suggesting its potential as a safe and effective treatment for erectile dysfunction.
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