Effect of pioglitazone on insulin receptors of skeletal muscles from high-fat-fed rats.

doi:10.1016/0026-0495(93)90016-H

Paper

DOI: 10.1016/0026-0495(93)90016-H

Effect of pioglitazone on insulin receptors of skeletal muscles from high-fat-fed rats.

Published Aug 1, 1993 · M. Iwanishi, M. Kobayashi

Metabolism: clinical and experimental

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Study Snapshot

Pioglitazone increases insulin sensitivity in high-fat-fed rats by activating tyrosine kinase activity, making it a useful drug for treating non-insulin-dependent diabetes mellitus with insulin resistance.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Citations

DOI: 10.1016/j.cdnut.2024.103768

Metabolic Effects of Short-Term High-Fat Intake Vary Depending on Dietary Amino Acid Composition

High-fat diets with different amino acid deficiencies can lead to different metabolic effects, with arginine deficiency inhibiting liver triglyceride accumulation and threonine reversing upregulation of serum LDL cholesterol.

2024·1citation·Hiroki Nishi et al.·Current Developments in Nutrition

Current Developments in Nutrition

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The Role of Sclerostin in Lipid and Glucose Metabolism Disorders.

Sclerostin plays a role in lipid and glucose metabolism disorders, potentially impacting obesity and diabetes treatment.

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DIFFERENT EXPERIMENTAL MODELS USED TO INDUCE DIABETES MELLITUS IN RODENTS: A REVIEW

Different experimental models show that high-fat diets, alloxan, and streptozotocin can induce diabetes in rats, with different mechanisms and potential therapeutic implications.

2019·1citation·R. Chakraborty et al.·International Journal of Current Pharmaceutical Research

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Effect of Fenugreek on Carbohydrate and Lipid Metabolisms of Rats Treated With Cypermethr in Combined With High-Fat-Diet and Low Dosestreptozotosin

Fenugreek etiolated sprouts and microgreens improve lipid metabolism and reduce blood glucose levels in rats treated with cypermethrin, while soaking seeds improves lipid metabolism and is non-toxic.

2019·1citation·Nagwa I. Koteb·Annals of Agricultural Science, Moshtohor

Annals of Agricultural Science, Moshtohor

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Clematis chinensis Extract Protects against Diabetic Nephropathy in Rats

Clematis chinensis extract significantly inhibits diabetic nephropathy-induced renal injury in rats, improving kidney function and reducing inflammation.

2016·3citations·Liang Xu et al.·Tropical Journal of Pharmaceutical Research

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