Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study.

doi:10.1016/0922-4106(91)90113-V

Paper

Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study.

Published Apr 25, 1991 · J. Kornhuber, J. Bormann, Marianne Hübers

European journal of pharmacology

Q1 SJR score

315

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7

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

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Study Snapshot

1-amino-adamantanes, including amantadine and memantine, generally produce their pharmacological effects through interaction with the NMDA-receptor-gated ion channel, potentially predicting their antiparkinsonian and antispastic activity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study.

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