Effects of felbamate on muscarinic and metabotropic-glutamate agonist-mediated responses and magnesium-free or 4-aminopyridine-induced epileptiform activity in guinea pig olfactory cortex neurons in vitro.

doi:10.1016/s0022-3565(25)13133-9

Paper

Effects of felbamate on muscarinic and metabotropic-glutamate agonist-mediated responses and magnesium-free or 4-aminopyridine-induced epileptiform activity in guinea pig olfactory cortex neurons in vitro.

Published Jun 1, 1996 · V. Libri, A. Constanti, M. Zibetti

The Journal of pharmacology and experimental therapeutics

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15

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2

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Abstract

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In Vitro Study

Study Snapshot

Felbamate can interfere with muscarinic and metabotropic-glutamate response generation and slow after-depolarization in olfactory cortical neurons, potentially blocking calcium influx through voltage-sensitive channels.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Effects of felbamate on muscarinic and metabotropic-glutamate agonist-mediated responses and magnesium-free or 4-aminopyridine-induced epileptiform activity in guinea pig olfactory cortex neurons in vitro.

References

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