Paper
Effects of Dietary Supplementation of Turmeric (Curcuma longa ) and Black Cumin Seed (Nigella sativa ) in Streptozotocin Induced Diabetic Rats
Published Jan 10, 2014 · S. El-Bahr, A. Al-Azraqi
International Journal of Biochemistry Research and Review
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Abstract
Aim: The objective of the present study was to investigate the antidiabetic effects of Turmeric (Curcuma longa) and Black cumin seed (Nigella sativa) either alone or in combination on blood glucose concentration, body weight, water and food intake and selected biochemical parameters of streptozotocin (STZ) induced diabetic rats. Study Design: Thirty five healthy adult albino rats kept on ordinary ration, received water ad libitum and divided into five groups (7 rats in each). Rats of first and second groups were non diabetic and diabetic respectively. Rats of 3-5 groups were diabetic and received Turmeric (1g/kg b.wt.), Black cumin seed (2g/kg b.wt.), half dose of black cumin seed and Turmeric as a mixture, respectively. All treatments were orally administered by intra-gastric intubations once a day for six weeks. Results: The present study revealed that, STZ experimental diabetes induced significant
Turmeric and Black cumin seed supplementation significantly improves blood glucose levels, body weight, water and food intake, and biochemical parameters in streptozotocin-induced diabetic rats.
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