Effects of Picrasma quassioides and its active constituents on Alzheimer's disease in vitro and in vivo.

doi:10.1016/j.bioorg.2019.103258

Paper

Effects of Picrasma quassioides and its active constituents on Alzheimer's disease in vitro and in vivo.

Published Nov 1, 2019 · Eryan Guo, Yunwei Hu, Tao Du

Bioorganic chemistry

Q1 SJR score

25

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1

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Abstract

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In Vitro Study

Study Snapshot

The EtOAc extract of Picrasma quassioides stems shows potential neuroprotective activities and improves memory and cognitive abilities in Alzheimer's disease mice, mainly due to suppressing neuroinflammatory and reducing A 1-42 deposition.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Effects of Picrasma quassioides and its active constituents on Alzheimer's disease in vitro and in vivo.

References

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