Paper
Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial.
Published Sep 1, 2015 · J. Bauer, S. Verlaan, I. Bautmans
Journal of the American Medical Directors Association
Q1 SJR score
522
Citations
24
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
RCT
Large Human Trial
Highly CitedStudy Snapshot
A vitamin D and leucine-enriched whey protein oral supplement improved muscle mass and lower-extremity function in sarcopenic older adults, potentially benefiting those unable to exercise.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
Handgrip strength does not represent an appropriate measure to evaluate changes in muscle strength during an exercise intervention program in frail older people.
Handgrip strength is not a valid measure to evaluate the efficacy of exercise intervention programs to increase muscle mass or strength in frail older people.
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Postprandial muscle protein synthesis is higher after a high whey protein, leucine-enriched supplement than after a dairy-like product in healthy older people: a randomized controlled trial
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Citations
Application of computed tomography body composition in patients with locally progressive gastric cancer undergoing radical surgery combined with prophylactic hyperthermic intraperitoneal chemotherapy.
Body composition and tumor characteristics are independent predictors of overall survival in patients with locally advanced gastric cancer undergoing radical surgery combined with p-HIPEC, providing reliable prognostic predictions.
2025·0citations·Wenzhi Wu et al.·Nutrition
Nutrition
Effects of aquatic exercise compared with land-based exercise on the body composition and function of older adults with sarcopenia: protocol for a randomised controlled trial
Aquatic exercise may improve body composition and function in older adults with sarcopenia compared to land-based exercise.
2025·0citations·PeiJie Sun et al.·BMJ Open
BMJ Open
Development and Validation of a Nutritional Frailty Phenotype for Older Adults Based on Risk Prediction Model: Results From a Population-Based Prospective Cohort Study.
A novel nutritional frailty phenotype, based on machine learning, suggests that nutritional supplementation combined with exercise may help prevent or delay adverse outcomes in older adults.
2024·0citations·Hongpeng Liu et al.·Journal of the American Medical Directors Association
Journal of the American Medical Directors Association
Effects of Nutritional Support with a Leucine-Enriched Essential Amino Acid Supplement on Body Composition, Muscle Strength, and Physical Function in Stroke Patients Undergoing Rehabilitation
A 3-month nutritional supplementation intervention may help increase BMI, preserve bone mineral content, and support physical activity levels in stroke patients undergoing rehabilitation without negatively affecting renal function.
2024·0citations·N. Nakagawa et al.·Nutrients
Nutrients
Addressing Inflammaging and Disease-Related Malnutrition: Adequacy of Oral Nutritional Supplements in Clinical Care
Most oral nutritional supplements meet daily energy and protein recommendations for age-related diseases, but need better regulation on optimal composition and production to effectively address disease-related malnutrition.
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Nutrients
Lessons learned from a combined, personalized lifestyle intervention in hospitalized patients at risk for sarcopenia: a feasibility study.
A combined, personalized lifestyle intervention had limited feasibility in hospitalized patients at risk for sarcopenia due to low recruitment and high dropout rates.
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Disability and rehabilitation
Optimizing the Preoperative Preparation of Sarcopenic Older People: The Role of Prehabilitation and Nutritional Supplementation before Knee Arthroplasty
Prehabilitation and dietary supplementation before knee arthroplasty can improve surgical resilience, muscle function, and quality of life in older sarcopenic individuals.
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Nutrients
Leucine Intake and Sarcopenia Indicators of an Elderly Group from the Metropolitan Region, Santiago de Chile, Who Participated in the Program for Complementary Food in Older People (PACAM)
Chilean elderly participating in PACAM have a high prevalence of sarcopenia and leucine deficiency, with no notable benefits from PACAM foods intake.
2024·1citation·Edson Bustos-Arriagada et al.·Nutrients
Nutrients