Structural elucidation of isocyanate-peptide adducts using tandem mass spectrometry

doi:10.1016/j.jasms.2009.04.016

Paper

Structural elucidation of isocyanate-peptide adducts using tandem mass spectrometry

Published May 3, 2009 · J. Hettick, Tinashe B. Ruwona, P. Siegel

Journal of the American Society for Mass Spectrometry

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21

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Abstract

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In Vitro Study

Study Snapshot

Isocyanates preferentially react with the N-terminus of model peptides, potentially contributing to allergic respiratory diseases through intra-molecular diisocyanate crosslinking.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Structural elucidation of isocyanate-peptide adducts using tandem mass spectrometry

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